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Chemometec NucleoCounter YC-100™ Yeast Cell Counter

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Automatic fluorescence cell counter that performs total and viability counting of yeast cells in 30 seconds. A practical, calibration-free solution for laboratories performing fermentation monitoring.

  • Automated cell count and viability analysis in 30 seconds
  • Calibration and cleaning not required with single-use NucleoCassette™
  • Measurement range: 5x10³ - 3x10⁶ cells/mL
  • Propidium iodide (PI) based DNA volumetric counting method
  • Compact design: 38x26x22 cm, 3 kg
  • Optional NucleoView™ software and printer support

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The NucleoCounter® YC-100™ is an automated cell counter that measures both total cell count and viability of yeast cells using propidium iodide (PI) staining combined with fluorescence microscopy and CCD camera technology. Designed for fermentation and bioprocess laboratories seeking rapid, reproducible results instead of manual counting.

The instrument requires no cleaning or calibration thanks to single-use NucleoCassette™ sampling cartridges, which reduces cross-contamination risk between samples and shortens analysis time. The DNA-based volumetric counting method delivers accurate results unaffected by medium debris or substrate aggregates—a critical advantage in complex fermentation environments.

Regular monitoring of cell count during fermentation studies assists researchers in determining intervention timing or harvest point for optimal product yield. Its compact footprint of 38x26x22 cm and 3 kg weight require minimal bench space; optional NucleoView™ software enables result documentation and reporting.

Technical Specifications

Manufacturer Chemometec (Denmark)
Catalog Number 900-0300
Load Volume 60 µl (NucleoCassette™)
Measurement Volume 1 µl (measurement chamber)
Analysis Time 30 seconds
Measurement Range 5×10³ – 3×10⁶ cells/mL
Dimensions (WxHxD) 38 x 26 x 22 cm
Weight 3 kg
Counting Method Fluorescence DNA counting with propidium iodide (PI)
Software NucleoView™ (optional)

Applications

  • Monitoring yeast cell count during fermentation processes
  • Yeast viability (viability) analysis
  • Bioprocess optimization and harvest timing determination

Frequently Asked Questions

What sample types can the YC-100™ be used with?
It is designed for total cell counting and viability measurement in yeast cell suspensions.
Does the instrument require calibration?
No, calibration or cleaning is not required thanks to the single-use NucleoCassette™ cartridge.
How long does it take to obtain results?
A single analysis is completed in approximately 30 seconds.