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AFG Scientific Guanidine Thiocyanate, Molecular Biology Grade 100 g

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Molecular Biology Grade guanidine thiocyanate at ≥99.5% purity. Used as a chaotropic agent in RNA/DNA extraction buffers, inhibits RNase/DNase activity.

  • ≥99.5% purity (Assay)
  • Molecular Biology Grade quality
  • Chaotropic agent that inhibits RNase/DNase activity
  • White crystalline powder, room temperature storage
  • Melting point 116-123 °C
  • 100 g package size

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Guanidine thiocyanate (Guanidinium thiocyanate) is one of the most frequently used chaotropic agents in nucleic acid isolation. AFG Scientific's Molecular Biology Grade product delivers reliable performance in RNA and DNA extraction protocols with ≥99.5% purity.

This compound denatures proteins during cell lysis, blocking RNase and DNase enzyme activity, thereby preserving the integrity of isolated nucleic acids. It is supplied as a white crystalline powder, can be stored at room temperature, and comes in a 100 g package suitable for laboratory use.

It is preferred in molecular biology laboratories for RNA/DNA isolation kits, lysis buffers, and viral RNA extraction protocols. Identified by CAS number 593-84-0 and MDL number MFCD00013027, this chemical can be safely used in quality control-critical applications.

Technical Specifications

CAS No 593-84-0
Purity ≥99.5% (Assay)
Molecular Formula CH5N3·HSCN
Molecular Weight 118.16
MDL No MFCD00013027
Appearance White crystalline powder
Melting Point 116-123 °C
Storage Temperature Room temperature
Package 100 g

Applications

  • Preparation of RNA/DNA extraction buffers
  • Cell lysis and nuclease inactivation
  • Viral RNA isolation protocols
  • Molecular biology kit manufacturing

Frequently Asked Questions

Why is guanidine thiocyanate used in RNA isolation?
Due to its chaotropic properties, it denatures proteins and inhibits RNase/DNase enzyme activity, protecting nucleic acid integrity.
How should the product be stored?
Store at room temperature in a dry, cool environment.
What is the purity level?
It has ≥99.5% purity as measured by assay, suitable for molecular biology applications.